116 SENSITIVITY TO PURINE ANTAGONISTS IN CHILDHOOD LEUKEMIA ASSESSED BY THE AUTOMATED MTT-ASSAY
نویسندگان
چکیده
منابع مشابه
Resistance to purine antagonists in experimental leukemia systems.
Resistance to purine analogs by loss of nucleotide-forming capacity was observed in a number of experimental tumor systems. Such resistance frequently was accom panied by loss of specific purine ribonucleotide pyrophosphorylase activities. How ever, it is evident that other mechanisms of resistance to purine analogs also exist both in mouse leukemia and in human leukemia. Attention was focused ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1988
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198807000-00140